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The active ingredient in Ambien, zolpidem, is a cyclopyrrolone compound that is structurally different from benzodiazepines and barbiturates, making it unique among sedative and hypnotic drugs. Ambien promotes rapid sleep onset and maintains sleep without disrupting sleep phases, enhancing overall sleep quality. Its effects begin about 30 minutes after ingestion and last 6 to 8 hours, matching the typical duration of natural sleep.
Compared to barbiturates and benzodiazepines, Ambien is far less likely to cause morning drowsiness or fatigue. Reviews suggest that Ambien may help reduce headaches, and in patients with bronchial asthma, it has been associated with fewer night and morning attacks, positively influencing both their duration and intensity. Ambien has a short half-life of 3.5 to 6 hours, and neither the drug nor its metabolites accumulate in the body, even with prolonged use.
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How to use
Ambien tablets should be taken only at bedtime. The standard daily dosage is 10 mg. For elderly patients, the initial dose may be reduced to 5 mg. In urgent situations, this can be increased to 10 mg.
The maximum daily dosage of Ambien is 10 mg, and its use should not exceed one month. For individuals with transient insomnia, a treatment period of 2-5 days is recommended, while those with situational insomnia may take the medication for 14-21 days.
If Ambien is used for several days, it can be discontinued abruptly. However, if treatment lasts more than a week, the dosage should be gradually reduced to minimize the risk of adverse reactions.
Side effects
In most cases, the medication does not produce negative reactions. However, some patients may experience the following undesirable effects while taking Ambien:
- Nausea, drowsiness, vomiting, headache, and diarrhea
- Paradoxical insomnia, abdominal pain, and agitation
- Dizziness, nightmares, and anterograde amnesia (the risk of which increases with dosage)
Additionally, very rare side effects may include:
Contraindications for Ambien use
According to the instructions, Ambien should not be prescribed in the following situations:
- Individual hypersensitivity to zolpidem or any other ingredients in the medication
- Sleep apnea syndrome (characterized by episodes of halted breathing during sleep)
- Moderate to severe myasthenia gravis
- Severe respiratory failure
- Severe renal failure
- Severe liver failure
- Individuals under 18 years of age
- Pregnancy
- Breastfeeding
Pay attention
Prolonged use of Ambien can lead to drug dependence, and patient reviews indicate the potential for withdrawal symptoms upon discontinuation. Combining Ambien with alcohol is strictly prohibited.
Ambien should not be used to treat depression, as it can mask the symptoms and potentially worsen the condition. The medication may cause general lethargy and slowed reaction times; therefore, patients should avoid activities that require quick reflexes, such as driving or operating machinery, during treatment.
Additionally, Ambien may interact with other medications, altering their effects. Any use of Ambien in conjunction with other drugs must be done under the supervision of a healthcare provider.