Antifungals
Antifungals: how we evaluate, when we prescribe, and safety checks. Start a confidential online consultation.
Overview
Antifungal medications combat infections caused by yeasts and molds. These organisms can affect the skin, nails, mucous membranes, or internal organs in immunocompromised individuals.
Uses
Indicated for candidiasis, ringworm (tinea), onychomycosis, and systemic fungal diseases such as cryptococcosis or aspergillosis. Common agents include fluconazole, itraconazole, terbinafine, and amphotericin B.Mechanism / Approach
Antifungals interfere with ergosterol synthesis, an essential fungal-cell-membrane component, or directly damage fungal cell walls, leading to cell death.Safety & Patient Considerations
Patients should take antifungals exactly as prescribed; early discontinuation can cause relapse. Possible adverse effects include nausea, rash, and elevated liver enzymes. Avoid alcohol during therapy to protect the liver.FAQ
Can antifungals treat yeast infections instantly?
Some respond within days, but severe cases need longer therapy.
Is topical therapy enough?
Mild infections may respond; systemic therapy is needed for deeper ones.
Can antifungals interact with other drugs?
Yes, especially with anticoagulants and certain antihistamines.