Online Sinequan (Doxepin)
Antidepressants • Educational only; not medical advice. Prescriptions at clinician discretion.

Overview
Doxepin, branded Sinequan, is a tricyclic antidepressant with potent antihistamine and sedative properties.
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Dr. Annie Casta, M.D., FAAP
Pediatrics Specialist
Providing compassionate pediatric care, wellness exams, and preventive treatments for children and adolescents.
Learn MoreDr. Jorge Trapaga, ARNP
Family Medicine & Primary Care
Specializing in primary care, chronic disease management, and wellness services for adults and families.
Meet Dr. TrapagaUses
Indicated for depression, anxiety, and insomnia. Low-dose formulations (3–6 mg) are approved specifically for sleep maintenance insomnia.Dosage & Administration
Depression/anxiety: 75–150 mg/day, up to 300 mg if needed. For insomnia: 3–6 mg nightly.Side Effects & Warnings
Drowsiness, weight gain, and dry mouth are common. Serious: QT prolongation, urinary retention, and confusion in elderly. Avoid MAOIs and alcohol.Patient Considerations
Take at bedtime. Adjust dose gradually.Ready for next steps?
FAQ
Is Sinequan mainly a sleep aid?
At low doses, yes.
Does it cause dependence?
No physical dependence, but tolerance may develop.
Can Sinequan cause weight gain?
Yes, due to antihistaminic effect.
Government / NIH sources
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