Online Phenergan (Promethazine)
Respiratory & Allergy • Educational only; not medical advice. Prescriptions at clinician discretion.
Overview
Promethazine, marketed as Phenergan, is a first-generation antihistamine of the phenothiazine class with strong sedative and antiemetic properties. It blocks H₁-histamine receptors and also exhibits anticholinergic and dopaminergic antagonism.
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Dr. Annie Casta, M.D., FAAP
Pediatrics Specialist
Providing compassionate pediatric care, wellness exams, and preventive treatments for children and adolescents.
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Family Medicine & Primary Care
Specializing in primary care, chronic disease management, and wellness services for adults and families.
Meet Dr. TrapagaUses
Indicated for allergy symptoms, motion sickness, nausea and vomiting, sedation, and adjunctive treatment of postoperative pain. Also used as a nighttime sleep aid.Dosage & Administration
Oral dose: 12.5–25 mg every 4–6 hours as needed; for motion sickness, 25 mg before travel. Parenteral and suppository forms are available. Children under two years should not receive it due to respiratory-depression risk.Side Effects & Warnings
Drowsiness, dry mouth, blurred vision, and constipation are common. Serious reactions: respiratory depression, neuroleptic-malignant-like syndrome, and tissue necrosis with extravasation (IV). Contraindicated with other CNS depressants or MAOIs.Patient Considerations
Avoid driving, alcohol, or sedatives. Use only short-term for sleep or nausea control.Ready for next steps?
FAQ
Is Phenergan safe for kids?
Not for children under two; older children require careful dosing.
Can I use Phenergan for anxiety?
It is not approved for anxiety; sedatives with fewer risks are preferred.
Does it help motion sickness?
Yes, it is effective when taken 30–60 minutes before travel.
Government / NIH sources
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