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Online Bactrim (Sulfamethoxazole and Primethoprim)

Antibiotics • Educational only; not medical advice. Prescriptions at clinician discretion.

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On this page: Overview FAQ Gov/NIH

Overview

Bactrim combines sulfamethoxazole and trimethoprim, providing synergistic inhibition of bacterial folate synthesis. This dual action makes it effective against a wide range of gram-positive and gram-negative bacteria.

Uses

Indicated for urinary-tract infections, bronchitis, traveler’s diarrhea, Pneumocystis jirovecii pneumonia (PCP), and some MRSA skin infections.

Dosage & Administration

Standard oral dose: 800 mg sulfamethoxazole / 160 mg trimethoprim every 12 hours for 10–14 days. Adjust for renal function. Take with water to prevent crystalluria.

Side Effects & Warnings

Common: nausea, rash, and loss of appetite. Serious: Stevens–Johnson syndrome, hyperkalemia, and blood dyscrasias. Contraindicated in sulfa allergy, pregnancy near term, and severe hepatic or renal disease.

Patient Considerations

Hydrate well. Avoid excessive sunlight due to photosensitivity. Report rash or sore throat immediately.

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FAQ

Is Bactrim an antibiotic?

Yes, it combines two antibiotics with complementary mechanisms.

Can I drink alcohol while taking Bactrim?

Alcohol may worsen side effects; avoid during therapy.

How soon will Bactrim work?

Improvement usually appears within 2–3 days of consistent dosing.

Government / NIH sources

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