Cymbalta (Duloxetine) Where To Buy
Antidepressants • Educational only; not medical advice. Prescriptions at clinician discretion.
Overview
Duloxetine, marketed as Cymbalta, is a serotonin–norepinephrine reuptake inhibitor (SNRI) used for depression, anxiety, neuropathic pain, and fibromyalgia. Approved in 2004, it enhances both serotonin and norepinephrine levels, helping regulate mood and pain perception.
Uses
Indicated for major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathy, chronic musculoskeletal pain, and fibromyalgia. It is also studied for urinary stress incontinence and chemotherapy-induced neuropathy.Dosage & Administration
Typical adult dose: 60 mg once daily; may start at 30 mg/day for one week. Maximum 120 mg/day. Capsules must be swallowed whole. Gradual tapering is required when discontinuing.Side Effects & Warnings
Common reactions include nausea, fatigue, dry mouth, and constipation. Serious risks: hepatotoxicity, serotonin syndrome, elevated blood pressure, and withdrawal effects. Avoid alcohol due to liver-toxicity potential. Contraindicated in severe hepatic or renal impairment.Patient Considerations
Full antidepressant effect may take 2–6 weeks. Blood-pressure monitoring is advised. Do not stop suddenly. Inform your clinician about all medications to prevent serotonin toxicity.Ready for next steps?
FAQ
Does Cymbalta help with pain as well as mood?
, it is approved for certain chronic pain syndromes and neuropathy.
Can Cymbalta cause weight changes?
Some patients experience mild weight loss early and gain later; effects vary.
How long should I take Cymbalta?
Duration depends on condition; continue until your doctor recommends tapering.
Government / NIH sources
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