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Online Effexor (Venlafaxine)

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On this page: Overview FAQ Gov/NIH

Overview

Venlafaxine, sold as Effexor, is a serotonin–norepinephrine reuptake inhibitor (SNRI) antidepressant first approved in 1993. It enhances neurotransmitter activity by inhibiting the reuptake of serotonin and norepinephrine in the brain.

Uses

Indicated for major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. Off-label applications include menopausal hot flashes and neuropathic pain.

Dosage & Administration

Initial dose: 75 mg/day (divided or extended-release once daily), increased gradually to 150–225 mg/day. Taper slowly when discontinuing to avoid withdrawal symptoms such as dizziness and irritability.

Side Effects & Warnings

Common: nausea, sweating, insomnia, dry mouth, and sexual dysfunction. Serious: hypertension, serotonin syndrome, and withdrawal effects with abrupt cessation. Monitor blood pressure during therapy.

Patient Considerations

Improvement may take several weeks. Avoid alcohol. Discuss any history of bipolar disorder, as antidepressants may trigger mania in predisposed individuals.

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FAQ

Is Effexor stimulating or sedating?

It may cause either effect depending on dosage and patient sensitivity.

Can Effexor cause withdrawal?

Yes, taper slowly to prevent dizziness, brain “zaps,” and mood swings.

How long before Effexor works?

Typically 2–4 weeks for noticeable improvement.

Government / NIH sources

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