Can I place an order without a prescription?

No. A telemedicine evaluation is required. Prescriptions are issued only when clinically appropriate.

Can you send my e‑prescription to a local pharmacy instead of delivery?

Yes. Tell your clinician your preferred pharmacy during the visit.

How do I rewrite/renew a prescription?

Use the Refill page to request a review. Your clinician will confirm safety, dosing, and timing.

How fast is shipping?

Most approved orders ship with tracking and typically arrive in 2–5 business days.

Do you prescribe controlled substances via telemedicine?

Generally no. We prioritize safer alternatives and coordinate in‑person care when required by safety or regulations.

Where can I read independent information about medications?

See NIH MedlinePlus, official labeling on NIH DailyMed, and approvals/history on the FDA Drugs@FDA database.

Online Tofranil (Imipramine)

Antidepressants • Educational only; not medical advice. Prescriptions at clinician discretion.

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On this page: Overview FAQ Gov/NIH

Overview

Imipramine, sold as Tofranil, is a tricyclic antidepressant (TCA) introduced in 1957. It inhibits serotonin and norepinephrine reuptake while antagonizing muscarinic and histamine receptors.

Uses

Treats major depressive disorder, panic disorder, and nocturnal enuresis in children.

Dosage & Administration

Depression: 75–150 mg/day, divided or at bedtime; up to 300 mg/day inpatient. Enuresis: 10–75 mg at bedtime. Taper gradually when discontinuing.

Side Effects & Warnings

Anticholinergic effects—dry mouth, constipation, blurred vision—plus orthostatic hypotension and sedation. Serious: arrhythmias, seizures, overdose toxicity. Contraindicated with MAOIs.

Patient Considerations

Monitor ECG in cardiac patients. Avoid alcohol.

Ready for next steps?

Consult a Doctor Rewrite / Renew Prescription

FAQ

How long until Tofranil works?

2–4 weeks.

Can children use it safely?

Yes, under strict supervision for enuresis.

Is overdose dangerous?

Yes, TCAs are highly toxic in overdose.

Government / NIH sources

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