Online Zyban (Bupropion Hydrochloride)
Antidepressants • Educational only; not medical advice. Prescriptions at clinician discretion.

Overview
Zyban contains bupropion hydrochloride, identical to Wellbutrin, repurposed for smoking cessation. It modulates dopamine and norepinephrine to reduce nicotine cravings.
Uses
Aids in quitting smoking by reducing withdrawal symptoms and cravings.Dosage & Administration
Begin 150 mg once daily for 3 days, then 150 mg twice daily for 7–12 weeks. Start 1–2 weeks before quit date.Side Effects & Warnings
Insomnia, dry mouth, and tremor are common. Seizure risk increases at high doses. Avoid combining with MAOIs or alcohol.Patient Considerations
Do not double missed doses. Avoid evening dosing to prevent insomnia.Ready for next steps?
Frequently asked questions
Is Zyban an antidepressant?
Yes, it’s the same molecule as Wellbutrin.
Can I smoke while taking Zyban?
Continue briefly until quit date, then stop.
Is weight gain likely?
Zyban may reduce post-cessation weight gain.
Government / NIH sources
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