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Online Diflucan (Fluconazole)

Antifungals • Educational only; not medical advice. Prescriptions at clinician discretion.

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On this page: Overview FAQ Gov/NIH

Overview

Diflucan is the brand name for fluconazole, a triazole antifungal medication. It works by inhibiting fungal cytochrome P450–dependent enzyme 14-α-demethylase, preventing ergosterol synthesis, a key component of fungal cell membranes. It is effective against a broad spectrum of yeasts and fungi, especially Candida species.

Uses

Diflucan is indicated for vaginal candidiasis, oropharyngeal and esophageal thrush, cryptococcal meningitis, and systemic fungal infections. It is also used prophylactically in immunocompromised patients, such as those undergoing chemotherapy or transplantation.

Dosage & Administration

Oral or IV dosing: 150 mg single dose for vaginal yeast infection; 100–400 mg daily for systemic infections. Duration depends on infection severity and site. Can be taken with or without food.

Side Effects & Warnings

Common: nausea, abdominal pain, headache, skin rash. Serious: hepatotoxicity, QT prolongation, Stevens–Johnson syndrome (rare). Avoid concurrent use with certain antihistamines, warfarin, or other QT-prolonging drugs.

Patient Considerations

Monitor liver function during prolonged therapy. Inform physicians of all current medications due to potential interactions. Avoid alcohol for liver protection.

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Frequently asked questions

Can Diflucan treat skin infections?

Yes, for yeast-related infections; not for dermatophytes like ringworm.

Is it safe in pregnancy?

Single 150 mg doses are acceptable, but long-term use should be avoided.

How quickly does it work?

Symptoms usually improve within 24–48 hours for vaginal infections.

Government / NIH sources

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