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Online Buspar (Buspirone)

Anxiety & Sleep • Educational only; not medical advice. Prescriptions at clinician discretion.

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Overview

Buspirone, sold as Buspar, is an anxiolytic unrelated to benzodiazepines. It acts as a partial agonist at serotonin 5-HT₁A receptors and modulates dopamine activity.

Uses

Treats generalized anxiety disorder and chronic anxiety symptoms. It lacks sedative, anticonvulsant, and muscle-relaxant properties, making it suitable for long-term therapy.

Dosage & Administration

Start at 7.5 mg twice daily, increasing every 2–3 days to 20–30 mg/day in divided doses (max 60 mg). Effects appear after 2–4 weeks.

Side Effects & Warnings

Dizziness, headache, and nausea are common. Rare: serotonin syndrome when combined with SSRIs or MAOIs. Avoid grapefruit juice (increases levels).

Patient Considerations

Take consistently with or without food. Unlike benzodiazepines, abrupt cessation does not cause withdrawal.

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FAQ

: Is Buspar addictive?

No, it has no dependency potential.

Can Buspar be taken with antidepressants?

Sometimes, but only under supervision.

Does Buspar make you sleepy?

It is generally non-sedating.

Government / NIH sources

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