Online Nexium (Esomeprazole)
Digestive & Reflux • Educational only; not medical advice. Prescriptions at clinician discretion.
Overview
Esomeprazole, branded Nexium, is a proton-pump inhibitor (PPI) that suppresses gastric-acid secretion by inhibiting the H⁺/K⁺-ATPase enzyme in parietal cells. It is the S-isomer of omeprazole, providing slightly improved bioavailability and acid control.
Uses
Treats gastroesophageal reflux disease (GERD), erosive esophagitis, peptic-ulcer disease, and Zollinger–Ellison syndrome. Also used in combination regimens for Helicobacter pylori eradication.Dosage & Administration
Typical adult regimen: 20–40 mg once daily for 4–8 weeks. Take at least 1 hour before meals. Long-term therapy may require periodic reassessment to minimize risk of nutrient deficiencies.Side Effects & Warnings
Common: headache, diarrhea, and abdominal pain. Long-term risks include vitamin B₁₂ deficiency, hypomagnesemia, and increased fracture probability. Rare: Clostridioides-associated diarrhea and kidney inflammation.Patient Considerations
Avoid abrupt discontinuation after prolonged use to reduce rebound acid hypersecretion. Inform your doctor of persistent abdominal pain or black stools.Ready for next steps?
Frequently asked questions
Can Nexium be used indefinitely?
Long-term use is possible under medical supervision but requires periodic review.
Is it better taken morning or night?
Morning before breakfast yields best acid control.
Does Nexium interact with other drugs?
It may alter absorption of medications needing acidic pH (e.g., ketoconazole, iron).
Government / NIH sources
Top Products
Meet our doctors
Licensed clinicians with evidence‑based prescribing. Learn about training, interests, and availability.