Online Imitrex (Sumatriptan)
Neurology & Migraine • Educational only; not medical advice. Prescriptions at clinician discretion.
Overview
Sumatriptan, marketed as Imitrex, is a selective serotonin (5-HT₁B/₁D) receptor agonist developed for acute migraine and cluster headache relief. It constricts cranial blood vessels and inhibits trigeminal nerve transmission, providing targeted pain relief.
Uses
Used for acute treatment of migraine attacks with or without aura and cluster headaches. It is not preventive but treats attacks after onset.Dosage & Administration
Available as oral tablets, nasal spray, and subcutaneous injection. Tablets: 50–100 mg at onset; may repeat after 2 hours (max 200 mg/day). Injectable form: 6 mg subcutaneously, repeatable once after 1 hour (max 12 mg/day).Side Effects & Warnings
Common: flushing, dizziness, and tightness in chest or throat. Serious: coronary vasospasm, myocardial infarction, or stroke in susceptible patients. Contraindicated in ischemic heart disease, uncontrolled hypertension, and hemiplegic migraine.Patient Considerations
Do not use within 24 hours of another triptan or ergotamine. Take only when migraine begins, not preventively.Ready for next steps?
FAQ
How fast does Imitrex work?
Injection acts within 10–15 minutes; tablets within 30–60 minutes.
Can Imitrex be used daily?
No—it should be used only for acute attacks, not chronically.
Is it safe for older adults?
Use caution in those with cardiovascular risk factors.
Government / NIH sources
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