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Online Revia (Naltrexone)

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On this page: Overview FAQ Gov/NIH

Overview

Naltrexone, sold as Revia (oral) and Vivitrol (injectable), is an opioid-receptor antagonist used in addiction medicine. Introduced in the 1980s, it blocks the euphoric and sedative effects of opioids and reduces alcohol craving.

Uses

Approved for opioid-dependence maintenance therapy after detoxification and for alcohol-dependence relapse prevention. It may also aid impulse-control disorders such as gambling addiction.

Dosage & Administration

Standard oral dose: 50 mg once daily. Injectable extended-release formulation delivers 380 mg intramuscularly monthly. Patients must be opioid-free for at least 7–10 days before starting to avoid precipitated withdrawal.

Side Effects & Warnings

Common: nausea, headache, fatigue, and insomnia. Serious: hepatotoxicity at high doses and precipitated withdrawal if opioids are still in the body. Contraindicated in acute hepatitis or liver failure.

Patient Considerations

Liver-function monitoring is essential. Carry medical ID indicating naltrexone therapy in case pain management is needed, as opioids will be ineffective.

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Frequently asked questions

Can Revia stop alcohol cravings immediately?

Craving reduction develops gradually over several days to weeks.

Is it safe to drink while on Revia?

Drinking while taking naltrexone lessens euphoria but can still harm the liver—avoid alcohol initially.

Can I use painkillers while on Revia?

Non-opioid analgesics like acetaminophen or NSAIDs are suitable; opioids will not work.

Government / NIH sources

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