Celebrex Online Where TO Buy
Pain & Inflammation • Educational only; not medical advice. Prescriptions at clinician discretion.
Overview
Celecoxib, marketed as Celebrex, is a selective cyclooxygenase-2 (COX-2) inhibitor developed to relieve inflammation and pain with less gastric irritation than older non-selective NSAIDs. Approved in 1998, it became one of the first COX-2–specific anti-inflammatory drugs. It blocks prostaglandin synthesis responsible for pain, swelling, and fever while sparing protective gastric COX-1 activity.
Uses
Celebrex is indicated for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, and primary dysmenorrhea. It may also reduce adenomatous colorectal polyps in hereditary polyposis, though this is an uncommon use due to cardiovascular risk.Dosage & Administration
Typical adult dosage: 200 mg daily or 100 mg twice daily for osteoarthritis; 200–400 mg daily for rheumatoid arthritis; 400 mg once, then 200 mg if needed for acute pain. Take with or without food; swallowing capsules whole is recommended. The lowest effective dose for the shortest duration should be used.Side Effects & Warnings
Most frequent reactions: dyspepsia, headache, hypertension, and upper-respiratory symptoms. Serious but rare events include gastrointestinal bleeding, myocardial infarction, and stroke. Celecoxib is contraindicated for patients allergic to sulfonamides or with recent coronary bypass surgery.Patient Considerations
Patients with cardiovascular disease should use the smallest possible dose and duration. Concurrent alcohol or corticosteroid use heightens GI risk. Kidney-impaired or elderly individuals need monitoring.Ready for next steps?
FAQ
Is Celebrex safer for the stomach than ibuprofen
Yes, selective COX-2 inhibition reduces ulcer risk, though bleeding can still occur.
Can I take Celebrex with aspirin?
Low-dose aspirin may be used for cardioprotection, but it negates some GI benefits—consult your doctor.
Does Celebrex cause weight gain?
Fluid retention can rarely lead to mild weight changes; report persistent swelling.
Government / NIH sources
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