Online Diclofenac
Pain & Inflammation • Educational only; not medical advice. Prescriptions at clinician discretion.
Overview
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) widely used for the relief of pain, inflammation, and fever. It inhibits both COX-1 and COX-2 enzymes, decreasing prostaglandin synthesis — chemicals responsible for pain and inflammation. Available in oral, topical, and injectable forms, it is marketed under brand names such as Voltaren, Cataflam, and Zipsor.
Uses
Indicated for musculoskeletal pain, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, menstrual cramps, and postoperative pain. Topical gels and patches are effective for localized joint and soft-tissue inflammation.Dosage & Administration
Typical oral dosing is 50 mg two or three times daily or 75 mg extended-release once daily. Topical formulations (1–2%) are applied 2–4 times daily to affected areas. Parenteral (IM/IV) forms are used for acute pain management.Side Effects & Warnings
Common side effects: stomach upset, heartburn, nausea, and edema. Serious: ulcers, GI bleeding, liver toxicity, and cardiovascular events with long-term use. Contraindicated in peptic ulcer disease, severe heart failure, or NSAID allergy.Patient Considerations
Patients should use the lowest effective dose for the shortest possible duration. Taking diclofenac with food or milk can minimize gastrointestinal irritation. Avoid alcohol and concurrent use of other NSAIDs.Ready for next steps?
Frequently asked questions
Is diclofenac stronger than ibuprofen?
It is often more potent and longer-acting, especially for arthritis pain.
Can I use diclofenac gel and pills together?
Yes, under supervision to avoid excess systemic exposure.
Is it safe for chronic use?
Long-term use increases cardiovascular and gastrointestinal risk; regular monitoring is essential.
Government / NIH sources
Top Products
Meet our doctors
Licensed clinicians with evidence‑based prescribing. Learn about training, interests, and availability.