Online Tramadol (Ultram)
Pain & Inflammation • Educational only; not medical advice. Prescriptions at clinician discretion.
Overview
Tramadol is a centrally acting synthetic analgesic approved in the 1990s. It has dual mechanisms: weak μ-opioid receptor agonism and inhibition of serotonin and norepinephrine reuptake. This combination provides moderate pain relief with a lower risk of respiratory depression compared to traditional opioids.
Uses
Indicated for moderate to moderately severe pain, both acute and chronic. It’s used after surgery, for musculoskeletal pain, and in certain neuropathic conditions. Extended-release forms treat persistent pain requiring around-the-clock management.Dosage & Administration
Immediate-release tablets: 50–100 mg every 4–6 hours as needed, not exceeding 400 mg/day. Extended-release: 100–300 mg once daily. Adjust for hepatic or renal impairment and in elderly patients.Side Effects & Warnings
Common: nausea, dizziness, constipation, and drowsiness. Serious: seizures, serotonin syndrome (especially when combined with SSRIs or MAOIs), and dependence with prolonged use. Abrupt discontinuation may cause withdrawal symptoms.Patient Considerations
Avoid alcohol and CNS depressants. Report confusion or unusual mood changes. Tramadol should be used at the lowest effective dose and for the shortest possible duration.Ready for next steps?
FAQ
Is Tramadol an opioid?
It is a synthetic opioid with additional serotonergic activity.
Can Tramadol be addictive?
Yes, dependence and tolerance can develop with long-term use.
Is it safe with antidepressants?
Caution—combination increases serotonin syndrome risk.
Government / NIH sources
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