Online Orlistat (Xenical)

Uses

Orlistat is indicated for weight loss and weight maintenance in overweight or obese adults with a body mass index (BMI) ≥ 30 kg/m² or ≥ 27 kg/m² in the presence of comorbidities such as diabetes, hypertension, or dyslipidemia. It also helps reduce the risk of weight regain after initial loss.

Dosage & Administration

The usual adult dose is 120 mg three times daily with each fat-containing meal; the OTC dose (Alli) is 60 mg three times daily. Orlistat should be taken during or up to one hour after the meal. If a meal is missed or contains no fat, the dose should be skipped. Patients should take a daily multivitamin supplement containing vitamins A, D, E, and K, at least 2 hours after orlistat.

Side Effects & Warnings

Common effects include oily stools, flatulence with discharge, and urgent bowel movements — all due to unabsorbed fat in the stool. Rare but serious side effects include liver injury, kidney stones, and fat-soluble vitamin deficiency. Contraindicated in chronic malabsorption syndrome or cholestasis.

Patient Considerations

Orlistat is most effective when combined with a reduced-calorie, low-fat diet. Patients should maintain adequate hydration and regular physical activity. It is not a stimulant, making it suitable for long-term therapy.