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Online Neurontin (Gabapentin)

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On this page: Overview FAQ Gov/NIH

Overview

Gabapentin, marketed as Neurontin, is an anticonvulsant and neuropathic-pain agent first approved in 1993. Structurally related to GABA but not acting directly on its receptors, it modulates calcium-channel activity in neurons, decreasing excitatory neurotransmitter release.

Uses

Indicated for partial seizures, postherpetic neuralgia, and neuropathic pain. Off-label uses include restless-legs syndrome, fibromyalgia, and anxiety.

Dosage & Administration

Initial dose: 300 mg once on day 1, then 300 mg twice on day 2, and 300 mg three times daily thereafter. Maintenance ranges 900–1800 mg/day in divided doses. Adjust for renal impairment. Capsules should be swallowed whole with water.

Side Effects & Warnings

Common: dizziness, somnolence, ataxia, and peripheral edema. Serious but uncommon: mood changes, suicidal ideation, and respiratory depression when combined with opioids. Abrupt cessation may precipitate seizures.

Patient Considerations

Take consistently; do not double doses. Avoid driving until effects are known. Report swelling or mood alterations.

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Frequently asked questions

Is Neurontin addictive?

Physical dependence is rare, but misuse has been reported at high doses.

How long before Neurontin relieves pain?

Pain relief often appears within one to two weeks.

Can I take Neurontin with alcohol?

No—both depress the central nervous system, increasing sedation risk.

Government / NIH sources

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